Regulated necrosis: the expanding network of non

Necrosis is the premature death of cells in living tissue and can be caused by external factors to the cell or tissue, such as infection, toxins, cancer, ...

There are several modes of regulated necrosis that are tightly related to cancer initiation and development, including necroptosis, ferroptosis, parthanatos, ...

Necroptosis is linked to rapid mitochondrial dysfunction that leads to the excessive production of reactive oxygen species.

The extrinsic pathway is activated by engagement of membrane receptors such as Tumor necrosis factor (TNF) receptor 1 (TNFR1), death ...

Necrosis is a form of cell injury which results in the premature death of cells in living tissue by autolysis. The term necrosis came about in the ... Avascular necrosis · Caseous necrosis · Liquefactive necrosis · Fat necrosis

This section describes the molecular events that initiate emerging pathways of regulated necrosis, including ferroptosis, oxytosis, ETosis, ...

Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.

Here we outline the recent discoveries into how the necrotic cell death execution pathway is engaged in many physiological and pathological outcome

Toll-like receptors activates programmed necrosis in macrophages through a receptor-interacting kinase-3–mediated pathway. Proc Natl Acad ...

Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.